Alice Margatroid is a puppeteer and magician. Her magic makes her dolls move freely, as if they were alive. Dolls have their own wills, and sometimes they might seem rather unmotivated when helping Alice out.

Medicine Melancholy is a newly born doll youkai. Her ability is thought to come from the poison of the lilies of the valley on Nameless Hill, where she was abandoned for a long time.

Medicine aims to liberate dolls from humans, probably because dolls are so important to her. Alice loves dolls a lot too, so the two would definitely hit it off if they met.

Reisen ended up joining the Great Airsoft Festival at the behest of Seiran, Ringo, and Nitori. Medicine was chosen as a medic to help Reisen. This is likely due to how Medicine normally provides Eirin with poison to help her make medicine. In a way, you could say she is the ultimate medic and helper.

Alice would definitely use her dolls to fight in the Great Airsoft Festival. If Medicine saw that, she would be sure to make it rain bullets to help the dolls that are so dear to her. Saving dolls would be more important to Medicine than a Team Moon Rabbit victory... But that's Medicine for you.